Some of our recent publications:
Our work published in Development (2012) has been highlighted by the editors of Science Signaling and was broadcast on several science-related websites disseminated to the public. Our findings in Nucleic Acids Research (2012) were included in a Cell review on chromatin and splicing regulation. Our studies are primarily supported by funds from the National Science Foundation.
Zraly, C.B., Zakkar, A., Hertenstein Perez, J., Ng, J., White, K.P., Slattery, M.G., and Dingwall, A.K. (2020) The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development. Nucleic Acids Res (academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa082/5735210?guestAccessKey=66c5045e-cca3-4de6-bc73-215231a0eaf6)
zraly_et_al._nar_2020_mlr_complex_in_cis-regulatory_programming-pdfa.pdf
Ford, D.J., Zraly, C.B., Hertenstein Perez, J., and Dingwall, A.K. (2020) The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate. Developmental Biology (uncorrected proof, https://authors.elsevier.com/sd/article/S0012-1606(20)30254-2)
ford_et_al._dev_biol_2020_bantan_regulation_in_context_of_cell_fate.pdf
Peiffer, D.S., Wyatt, D., Zlobin, A. Piracha, A., Ng, J., Dingwall, A.K., Albain, K.S. and Osipo, C. (2019) DAXX is a critical mediator of estrogen action to suppress tumor initiating cells in estrogen-positive breast cancer. Cancer Research 19:4965-497 (https://cancerres.aacrjournals.org/content/79/19/4965.long). peiffer_et_al._cancer_res_2019_pdf-a.pdf
Fagan, R. and Dingwall, A.K. (2019) COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer. Cancer Letters 458:56-65. doi: 10.1016/j.canlet.2019.05.024. Epub 2019 May 22 fagan_and_dingwall_2019_cancer_letters_pdf-a.pdf
Ford, D.J. and Dingwall, A.K. (2015) The cancer COMPASS: Navigating the functions of MLL complexes in cancer. Cancer Genet doi: 10.1016/j. cancergen.2015.01.005 [Epub ahead of print]. PDF version
Chauhan, C., Zraly, C.B. and Dingwall, A.K. (2013) The Drosophila COMPASS-like CMI/TRR coactivator complex regulates dpp/BMP signaling in pattern formation. Dev Biol 380: 185-198. PDF version
Curtis, B.J., Zraly, C.B. and Dingwall, A.K. (2013) Drosophila LSD1-CoREST demethylase complex regulates DPP/TGFb signaling during wing development. genesis 51: 16-31. http://onlinelibrary.wiley.com/doi/10.1002/dvg.22346/full
Chauhan, C., Zraly, C.B., Parilla, M., Diaz, M.O. and Dingwall, A.K. (2012) Histone recognition and nuclear receptor coactivator functions of Drosophila Cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3. Development 139: 1997-2008. PDF version
Zraly, C.B. and Dingwall, A.K. (2012) The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit. Nucleic Acids Res 40: 5975-5987. PDF version
*Trivedi, R., Zraly, C.B. and Dingwall, A.K. (2012) Comparison of Drosophila CMI to human ALR/MLL2. J Exper Secondary Sci 2:20-24. (*High school student, Illinois Math and Science Academy, Aurora, IL) trivedi_et_al.pdf
Curtis, B.J., Zraly, C.B., Marenda, D.R. and Dingwall, A.K. (2011) Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. Dev Biol 350: 534-547. http://dx.doi.org/10.1016/j.ydbio.2010.12.001
Toth, G., Zraly, C.B., Thomson, T.L., Jones, C., Lapetino, S., Muraskas, J., Zhang, J. and Dingwall, A.K. (2011) Congenital anomalies and rhabdoid tumor associated with 22q11 germline deletion and somatic inactivation of the SMARCB1 tumor suppressor. Genes, Chrom & Cancer 50: 379-388. http://onlinelibrary.wiley.com/doi/10.1002/gcc.20862/pdf
Our work published in Development (2012) has been highlighted by the editors of Science Signaling and was broadcast on several science-related websites disseminated to the public. Our findings in Nucleic Acids Research (2012) were included in a Cell review on chromatin and splicing regulation. Our studies are primarily supported by funds from the National Science Foundation.
Zraly, C.B., Zakkar, A., Hertenstein Perez, J., Ng, J., White, K.P., Slattery, M.G., and Dingwall, A.K. (2020) The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development. Nucleic Acids Res (academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa082/5735210?guestAccessKey=66c5045e-cca3-4de6-bc73-215231a0eaf6)
zraly_et_al._nar_2020_mlr_complex_in_cis-regulatory_programming-pdfa.pdf
Ford, D.J., Zraly, C.B., Hertenstein Perez, J., and Dingwall, A.K. (2020) The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate. Developmental Biology (uncorrected proof, https://authors.elsevier.com/sd/article/S0012-1606(20)30254-2)
ford_et_al._dev_biol_2020_bantan_regulation_in_context_of_cell_fate.pdf
Peiffer, D.S., Wyatt, D., Zlobin, A. Piracha, A., Ng, J., Dingwall, A.K., Albain, K.S. and Osipo, C. (2019) DAXX is a critical mediator of estrogen action to suppress tumor initiating cells in estrogen-positive breast cancer. Cancer Research 19:4965-497 (https://cancerres.aacrjournals.org/content/79/19/4965.long). peiffer_et_al._cancer_res_2019_pdf-a.pdf
Fagan, R. and Dingwall, A.K. (2019) COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer. Cancer Letters 458:56-65. doi: 10.1016/j.canlet.2019.05.024. Epub 2019 May 22 fagan_and_dingwall_2019_cancer_letters_pdf-a.pdf
Ford, D.J. and Dingwall, A.K. (2015) The cancer COMPASS: Navigating the functions of MLL complexes in cancer. Cancer Genet doi: 10.1016/j. cancergen.2015.01.005 [Epub ahead of print]. PDF version
Chauhan, C., Zraly, C.B. and Dingwall, A.K. (2013) The Drosophila COMPASS-like CMI/TRR coactivator complex regulates dpp/BMP signaling in pattern formation. Dev Biol 380: 185-198. PDF version
Curtis, B.J., Zraly, C.B. and Dingwall, A.K. (2013) Drosophila LSD1-CoREST demethylase complex regulates DPP/TGFb signaling during wing development. genesis 51: 16-31. http://onlinelibrary.wiley.com/doi/10.1002/dvg.22346/full
Chauhan, C., Zraly, C.B., Parilla, M., Diaz, M.O. and Dingwall, A.K. (2012) Histone recognition and nuclear receptor coactivator functions of Drosophila Cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3. Development 139: 1997-2008. PDF version
Zraly, C.B. and Dingwall, A.K. (2012) The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit. Nucleic Acids Res 40: 5975-5987. PDF version
*Trivedi, R., Zraly, C.B. and Dingwall, A.K. (2012) Comparison of Drosophila CMI to human ALR/MLL2. J Exper Secondary Sci 2:20-24. (*High school student, Illinois Math and Science Academy, Aurora, IL) trivedi_et_al.pdf
Curtis, B.J., Zraly, C.B., Marenda, D.R. and Dingwall, A.K. (2011) Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. Dev Biol 350: 534-547. http://dx.doi.org/10.1016/j.ydbio.2010.12.001
Toth, G., Zraly, C.B., Thomson, T.L., Jones, C., Lapetino, S., Muraskas, J., Zhang, J. and Dingwall, A.K. (2011) Congenital anomalies and rhabdoid tumor associated with 22q11 germline deletion and somatic inactivation of the SMARCB1 tumor suppressor. Genes, Chrom & Cancer 50: 379-388. http://onlinelibrary.wiley.com/doi/10.1002/gcc.20862/pdf
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